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Home / Primary Antibodies

CYP27A1 Antibody

SKU : BHA10558118

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA695994
Alternative Names	25-hydroxylase; 5-beta-cholestane-3-alpha; 7-alpha; 12-alpha-triol 27-hydroxylase; CP27A
Categories	Primary Antibodies
Clonality	polyclonal
Description	Catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity.Cali J.J., J. Biol. Chem. 266:7774-7778(1991).Guo Y.-D., Proc. Natl. Acad. Sci. U.S.A. 90:8668-8672(1993).Leitersdorf E., J. Clin. Invest. 91:2488-2496(1993).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human Cytochrome P450 27A1.
Involvement In Disease	Cerebrotendinous xanthomatosis (CTX)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity. Cali J.J., J. Biol. Chem. 266:7774-7778(1991). Guo Y.-D., Proc. Natl. Acad. Sci. U.S.A. 90:8668-8672(1993). Leitersdorf E., J. Clin. Invest. 91:2488-2496(1993).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total Cytochrome P450 27A1 protein.
Subcellular Location	Mitochondrion membrane

Uniprot	Q02318
Database Links	HGNC:2605 OMIM:213700 KEGG:hsa:1593 STRING:9606.ENSP00000258415 UniGene:Hs.516700
Function	Catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity.
Pathway	PPAR signaling pathway Cholesterol metabolism
Protein Families	Cytochrome P450 family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558118	CSB-PA695994	100ul	$297		Add to Cart

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