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Home / Primary Antibodies

CYP26A1 Antibody

SKU : BHA10558117

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA288324
Alternative Names	Cytochrome P450 26A1; EC 1.14.-.-; Retinoic acid-metabolizing cytochrome; P450 retinoic acid-inactivating 1; P450RAI
Categories	Primary Antibodies
Clonality	polyclonal
Description	Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18-hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA.White J.A., J. Biol. Chem. 272:18538-18541(1997).Sonneveld E., Cell Growth Differ. 9:629-637(1998).ova-Griffin M.E., Biochem. Biophys. Res. Commun. 252:487-491(1998).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human Cytochrome P450 26A1.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18-hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA. White J.A., J. Biol. Chem. 272:18538-18541(1997). Sonneveld E., Cell Growth Differ. 9:629-637(1998). ova-Griffin M.E., Biochem. Biophys. Res. Commun. 252:487-491(1998).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total Cytochrome P450 26A1 protein.
Subcellular Location	Endoplasmic reticulum membrane, Peripheral membrane protein, Microsome membrane, Peripheral membrane protein

Uniprot	O43174
Database Links	HGNC:2603 OMIM:602239 KEGG:hsa:1592 STRING:9606.ENSP00000224356 UniGene:Hs.150595
Function	Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18-hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA.
Protein Families	Cytochrome P450 family
Tissue Specificity	Highest levels in adult liver, heart, pituitary gland, adrenal gland, placenta and regions of the brain.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558117	CSB-PA288324	100ul	$297		Add to Cart

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