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Home / Primary Antibodies

CYP11B1/CYP11B2 Antibody

SKU : BHA10558814

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA070172
Alternative Names	C11B1; CPN1; CYP11B; CYP11B1; CYPXIB1
Categories	Primary Antibodies
Clonality	polyclonal
Description	Has steroid 11-beta-hydroxylase activity. In addition to this activity, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P450 XIB.Mornet E., J. Biol. Chem. 264:20961-20967(1989).Kawamoto T., FEBS Lett. 269:345-349(1990).Nusbaum C., Nature 439:331-335(2006).
Host	Rabbit
Immunogen	Synthesized peptide derived from C-terminal of Human Cytochrome P450 11B1/2.
Involvement In Disease	Adrenal hyperplasia 4 (AH4); Hyperaldosteronism, familial, 1 (HALD1)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Has steroid 11-beta-hydroxylase activity. In addition to this activity, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P450 XIB. Mornet E., J. Biol. Chem. 264:20961-20967(1989). Kawamoto T., FEBS Lett. 269:345-349(1990). Nusbaum C., Nature 439:331-335(2006).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total Cytochrome P450 11B1/2 protein.
Subcellular Location	Mitochondrion membrane

Uniprot	P15538
Database Links	HGNC:2591 OMIM:103900 KEGG:hsa:1584 STRING:9606.ENSP00000292427 UniGene:Hs.184927
Function	Has steroid 11-beta-hydroxylase activity. In addition to this activity, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P450 XIB.
Protein Families	Cytochrome P450 family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558814	CSB-PA070172	100ul	$297		Add to Cart

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