Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone.Chung B.-C., Proc. Natl. Acad. Sci. U.S.A. 83:8962-8966(1986).Morohashi K., J. Biochem. 101:879-887(1987).Ota T., Nat. Genet. 36:40-45(2004).
Host
Rabbit
Immunogen
Synthesized peptide derived from C-terminal of Human Cytochrome P450 11A1.
Involvement In Disease
Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone.
Chung B.-C., Proc. Natl. Acad. Sci. U.S.A. 83:8962-8966(1986). Morohashi K., J. Biochem. 101:879-887(1987). Ota T., Nat. Genet. 36:40-45(2004).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total Cytochrome P450 11A1 protein.