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Home / Primary Antibodies

Cyclin T1 Antibody / CCNT1 (F54551)

SKU : BHA17103020

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NSJ Bioreagents

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Mfr.No.	F54551, F54551-0.08ML, F54551-0.4ML
Antigen	Cyclin T1
Clonality	Polyclonal
Description	CCNT1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 253-281 from the human protein was used as the immunogen for the CCNT1 antibody.
Isotype	Ig
Predicted Reactivity	Human, Mouse
Reactivity	Human, Mouse
Recombinant	No

Uniprot	O60563

Format	Purified
Purification	Antigen affinity purified
Storage	Aliquot the CCNT1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, FACS
Dilution	Western blot: 1:500-1:2000, Flow cytometry: 1:25 (1x10e6 cells)

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17103020-1	F54551-0.08ML	0.08ml	$165		Add to Cart
BHA17103020-2	F54551-0.4ML	0.4ml	$379		Add to Cart

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