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Home / Primary Antibodies

CUX1 Antibody

SKU : BHA10557850

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA273037
Alternative Names	CCAAT displacement protein; CDP; Cut-like 1;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator By similarity.Neufeld E.J., Nat. Genet. 1:50-55(1992).Gloeckner G., Genome Res. 8:1060-1073(1998).Rong Zeng W., Gene 241:75-85(2000).
Host	Rabbit
Immunogen	Synthesized peptide derived from N-terminal of Human CUTL1.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator By similarity. Neufeld E.J., Nat. Genet. 1:50-55(1992). Gloeckner G., Genome Res. 8:1060-1073(1998). Rong Zeng W., Gene 241:75-85(2000).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total CUTL1 protein.
Subcellular Location	Nucleus

Uniprot	P39880
Database Links	HGNC:2557 OMIM:116896 STRING:9606.ENSP00000353401 UniGene:Hs.191482
Function	Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator (By similarity).
Protein Families	CUT homeobox family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557850	CSB-PA273037	100ul	$297		Add to Cart

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