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Home / Antibodies

CTSD Antibody / Cathepsin D (V7644)

SKU : BHA17116774

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NSJ Bioreagents

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Mfr.No.	V7644, V7644-20UG, V7644-100UG
Antigen	CTSD
Clonality	Monoclonal
Description	Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 52kDa preprocathepsin D that is cleaved and glycosylated to form a 48kDa procathepsin D and then further cleaved to produce 34kDa and 14kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.
Formulation	0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Host	Mouse
Immunogen Region	Amino acids 104-250 were used as the immunogen of the Cathepsin D antibody.
Isotype	IgG1,kappa
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No
Subcellular Location	Cytoplasmic

Uniprot	P07339
Clone No	CTPD-1

Concentration	0.2 mg/ml
Format	Purified
Purification	Protein G affinity chromatography
Storage	Store the Cathepsin D antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Applications	IHC-P, WB
Dilution	Immunohistochemistry (FFPE): 0.5-1ug/ml,Western blot: 1-2ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17116774-1	V7644-20UG	20ug	$219		Add to Cart
BHA17116774-2	V7644-100UG	100ug	$499		Add to Cart

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