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Home / Primary Antibodies

CTLA-4 Antibody / CD152 (RQ6465)

SKU : BHA17122726

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NSJ Bioreagents

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Mfr.No.	RQ6465
Clonality	Polyclonal (rabbit origin)
Description	CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4), also known as CD152, is a protein receptor that down regulates the immune system. It is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Blockade of CTLA4 expression in vitro augmented HIV-specific CD4-positive T-cell function.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An E. coli-derived human protein (amino acids N110-N223) was used as the immunogen for the CTLA4 antibody.
Isotype	Rabbit IgG
Species Reactivity	Human
Note	Optimal dilution of the CTLA4 antibody should be determined by the researcher.

Uniprot	P16410

Format	Antigen affinity purified
Purity	Affinity purified
Storage	After reconstitution, the CTLA4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	IHC-P, Direct ELISA
Description	Immunohistochemistry (FFPE): 2-5ug/ml,Direct ELISA: 0.1-0.5ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17122726	RQ6465	100ug	$419		Add to Cart

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