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Home / Antibodies

CSPG4 Antibody / NG2 (V7819SAF)

SKU : BHA17126972

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NSJ Bioreagents

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Mfr.No.	V7819SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin. Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins. May promote retraction fiber formation and cell polarization through Rho GTPase activation. May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades. (UniProt)
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A 375P cells crude extract was used as the immunogen for this CSPG4 antibody
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the antibody should be determined by the researcher.

Uniprot	Q6UVK1

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the CSPG4 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IF, IHC-P
Description	Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/cspg4-antibody-ng2-lhm-2-v7819" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17126972	V7819SAF-100UG	100 ug	$499		Add to Cart

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