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Home / Antibodies

CREBZF Antibody

SKU : BHA10559360

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA035026
Alternative Names	CREB/ATF bZIP transcription factor; Host cell factor-binding transcription factor Zhangfei; HCF-binding transcription factor Zhangfei; CREBZF; ZF
Categories	Primary Antibodies
Clonality	polyclonal
Description	Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells.Lu R., Nucleic Acids Res. 28:2446-2454(2000).The MGC Project Team, Genome Res. 14:2121-2127(2004).Misra V., J. Biol. Chem. 280:15257-15266(2005).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human CREBZF.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells. Lu R., Nucleic Acids Res. 28:2446-2454(2000). The MGC Project Team, Genome Res. 14:2121-2127(2004). Misra V., J. Biol. Chem. 280:15257-15266(2005).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total CREBZF protein.
Subcellular Location	Nucleus

Uniprot	Q9NS37
Database Links	HGNC:24905 OMIM:606444 KEGG:hsa:58487 STRING:9606.ENSP00000433459 UniGene:Hs.535319
Function	Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells.
Protein Families	BZIP family, ATF subfamily
Tissue Specificity	In adults, expressed most abundantly in heart, liver and skeletal muscle, moderately abundant in kidney and pancreas, and barely detectable in lung. In fetal tissues, expressed most abundantly in kidney and very low amounts in heart, lung and liver.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IF

Description

ELISA ; WB ; IF, WB ; ELISA ; IF

Dilution

WB	1:500-1:3000
IF	1:100-1:500

Tested Application

ELISA,WB,IF;WB:1:500-1:3000,IF:1:100-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559360	CSB-PA035026	100ul	$297		Add to Cart

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