Rabbit Anti-Human Cpn10 Polyclonal

Mfr.No.	SPC-193, SPC-193D, SPC-193C, SPC-193D-A390, SPC-193D-A488, SPC-193D-A594, SPC-193D-ALP, SPC-193D-APC, SPC-193D-BI, SPC-193D-FITC, SPC-193D-HRP, SPC-193D-PCP, SPC-193D-RPE, SPC-193S
Immunogen Species	Human
Alternative Names	10kDa Chaperonin Antibody, Chaperonin 10 Antibody, Cpn 10 Antibody, EPF Antibody, GROES Antibody, Heat Shock 10kD protein1 Antibody, HSP10 Antibody, HSPE1 Antibody
Categories	Antibodies
Cellular Localization	Mitochondrion, Mitochondrion Matrix
Certificate Of Analysis	1 ug/ml of SPC-193 was sufficient for detection of Cpn10 in 10 ug of Hela lysates by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Description	Rabbit Anti-Human Cpn10 Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	Human Cpn10 peptide AA 91-101, Homo Sapiens (Human)
Immunogen Region	Human Cpn10 peptide AA 91-101
Launch Date	2009/12/01
Net Weight (g)	0.1
Reactivity	Guinea Pig, African clawed frog, Dog, Pig, Rat, Sheep, Mouse, Human, Bovine, Rabbit
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Mouse, Rat, Bovine, Dog, Guinea Pig, Pig, Rabbit, Sheep, Xenopus, Human

Swissprot	P61604
Accession Number	NP_002148.1
Gene Id	3336
Target	Cpn10
Research Area	Cancer, Heat Shock, Cell Signaling, Chaperone Proteins, Metabolism, Mitochondrial Metabolism, Mitochondrial Markers, Protein Trafficking

Buffer	PBS pH7.3, 0.02% sodium azide
Concentration	1 mg/ml
Dilutions	WB (1:1000), IHC (1:100); optimal dilutions for assays should be determined by the user.
Purification	Protein A Purified
Scientific Background	Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding of polypeptides. Cpn10 and Cpn60 both exhibit sevenfold axis of symmetry and function as a team in the protein folding and assembly process (1). Cpn10 has been located in human platelets, but is also present in human maternal serum (2, 3). It has been reported that human Cpn10 is identical with early pregnancy factor, which is involved in control over cell growth and development. This identification suggest that Cpn10 may act like a hormone in stressful situations such as pregnancy (4).
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects ~ 10kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.3, 0.02% sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	ELISA, IHC, IP, WB, ICC/IF
Description	WB ; IHC ; ICC ; IF ; IP ; ELISA
Dilution	WB (1:1000), IHC (1:100); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

Reference	1. Velez-Granell C.S., et al. (1994) J of Cell Science. 107(3): 539-549. 2. Morton H., Hegh V., and Clunie G.J.A. (1974) Nature (London) 249: 459-460. 3. Cavanagh A.C., and Morton H. (1994) Eur. J. Biochem. 222: 551-560. 4. Minto M., et al. (1998) Molecular Cell Research. 1403 (2): 151-157.

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11907258-1	SPC-193D	Unconjugated	100 ug	$242	Add to Cart
BHA11907258-2	SPC-193C	Unconjugated	25 ug	$132	Add to Cart
BHA11907258-3	SPC-193D-A390	ATTO 390	100 ug	$296	Add to Cart
BHA11907258-4	SPC-193D-A488	ATTO 488	100 ug	$295	Add to Cart
BHA11907258-5	SPC-193D-A594	ATTO 594	100 ug	$295	Add to Cart
BHA11907258-6	SPC-193D-ALP	Alkaline Phosphatase	100 ug	$288	Add to Cart
BHA11907258-7	SPC-193D-APC	APC	100 ug	$294	Add to Cart
BHA11907258-8	SPC-193D-BI	Biotin	100 ug	$290	Add to Cart
BHA11907258-9	SPC-193D-FITC	FITC	100 ug	$286	Add to Cart
BHA11907258-10	SPC-193D-HRP	HRP	100 ug	$282	Add to Cart
BHA11907258-11	SPC-193D-PCP	PerCP	100 ug	$294	Add to Cart
BHA11907258-12	SPC-193D-RPE	RPE	100 ug	$292	Add to Cart
BHA11907258-13	SPC-193S	Unconjugated	12 ug	$44	Add to Cart

Cpn10 Antibody - SPC-193