anaphylatoxin inactivator; arginine carboxypeptidase; carboxypeptidase N 1; carboxypeptidase N catalytic; carboxypeptidase N polypeptide 1 50 kD
Categories
Primary Antibodies
Clonality
polyclonal
Description
Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation.Gebhard W., Eur. J. Biochem. 178:603-607(1989).The MGC Project Team; Genome Res. 14:2121-2127(2004).Skidgel R.A., Biochem. Biophys. Res. Commun. 154:1323-1329(1988).
Host
Rabbit
Immunogen
Synthesized peptide derived from C-terminal of Human CPN1.
Involvement In Disease
Carboxypeptidase N deficiency (CPND)
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation.
Gebhard W., Eur. J. Biochem. 178:603-607(1989). The MGC Project Team; Genome Res. 14:2121-2127(2004). Skidgel R.A., Biochem. Biophys. Res. Commun. 154:1323-1329(1988).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total CPN1 protein.
Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation.
Protein Families
Peptidase M14 family
Tissue Specificity
Synthesized in the liver and secreted in plasma.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.