Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins.Tan F., J. Biol. Chem. 264:13165-13170(1989).Skidgel R.A., Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.Bektas A., Diabetes 50:204-208(2001).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human CPM.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins.
Tan F., J. Biol. Chem. 264:13165-13170(1989). Skidgel R.A., Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases. Bektas A., Diabetes 50:204-208(2001).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total CPM protein.
Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins.
Protein Families
Peptidase M14 family
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.