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Home / Primary Antibodies

Cortactin Antibody (F53608)

SKU : BHA17119820

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NSJ Bioreagents

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Mfr.No.	F53608-0.1ML
Clonality	Monoclonal (mouse origin)
Description	This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.
Formulation	In ascites with 0.09% sodium azide
Host	Mouse
Immunogen Region	Purified His-tagged Cortactin protein fragment was used to produced this monoclonal Cortactin antibody.
Isotype	Mouse IgM
Species Reactivity	Human
Note	Titration of the Cortactin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Uniprot	Q14247

Format	Ascites
Purity	Ascites
Storage	Aliquot the Cortactin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, ELISA
Description	Weste blot: 1:1000-1:8000

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119820	F53608-0.1ML	0.1 ml	$379		Add to Cart

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