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Home / Antibodies

CNTN6 Antibody

SKU : BHA10558361

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA973774
Alternative Names	contactin 6; contactin-6; NB3; neural adhesion molecule; neural recognition molecule NB-3
Categories	Primary Antibodies
Clonality	polyclonal
Description	Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination By similarity.Kamei Y., J. Neurosci. Res. 51:275-283(1998).The MGC Project Team, Genome Res. 14:2121-2127(2004).Mayya V., Sci. Signal. 2:RA46-RA46(2009).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human CNTN6.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination By similarity. Kamei Y., J. Neurosci. Res. 51:275-283(1998). The MGC Project Team, Genome Res. 14:2121-2127(2004). Mayya V., Sci. Signal. 2:RA46-RA46(2009).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total CNTN6 protein.
Subcellular Location	Cell membrane, Lipid-anchor, GPI-anchor

Uniprot	Q9UQ52
Database Links	HGNC:2176 OMIM:607220 KEGG:hsa:27255 STRING:9606.ENSP00000341882 UniGene:Hs.387300
Function	Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination (By similarity).
Protein Families	Immunoglobulin superfamily, Contactin family
Tissue Specificity	Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558361	CSB-PA973774	100ul	$297		Add to Cart

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