Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.The MGC Project Team; Genome Res. 14:2121-2127(2004).Distler M., Neuropharmacology 33:1275-1282(1994).Sjoeblom T., Science 314:268-274(2006).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human CNGA2.
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.
The MGC Project Team; Genome Res. 14:2121-2127(2004). Distler M., Neuropharmacology 33:1275-1282(1994). Sjoeblom T., Science 314:268-274(2006).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total CNGA2 protein.
Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.