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Home / Antibodies

CLDN8 Antibody

SKU : BHA10558350

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA104901
Alternative Names	claudin 8; CLDN8;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Plays a major role in tight junction-specific obliteration of the intercellular space By similarity.Clark H.F., Genome Res. 13:2265-2270(2003).Hattori M., Nature 405:311-319(2000).Dube E., Biol. Reprod. 76:1034-1044(2007).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human CLDN8.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Plays a major role in tight junction-specific obliteration of the intercellular space By similarity. Clark H.F., Genome Res. 13:2265-2270(2003). Hattori M., Nature 405:311-319(2000). Dube E., Biol. Reprod. 76:1034-1044(2007).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total CLDN8 protein.
Subcellular Location	Cell junction, tight junction, Cell membrane, Multi-pass membrane protein

Uniprot	P56748
Database Links	HGNC:2050 OMIM:611231 KEGG:hsa:9073 STRING:9606.ENSP00000286809 UniGene:Hs.162209
Function	Tight-junction protein required for paracellular chloride transport in the kidney. Mediates recruitment of CLDN4 to tight junction in the kidney. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Protein Families	Claudin family
Tissue Specificity	Expressed in the epididymis, mainly in the caput segment.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558350	CSB-PA104901	100ul	$297		Add to Cart

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