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Home / Antibodies

CLCN7 Antibody

SKU : BHA10558336

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA212493
Alternative Names	Chloride channel protein 7; ClC-7;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen.Rae J.L., Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases.Ota T., Nat. Genet. 36:40-45(2004).Martin J., Nature 432:988-994(2004).
Host	Rabbit
Immunogen	Synthesized peptide derived from N-terminal of Human CLCN7.
Involvement In Disease	Osteopetrosis, autosomal recessive 4 (OPTB4); Osteopetrosis, autosomal dominant 2 (OPTA2); Osteopetrosis, autosomal recessive 2 (OPTB2)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen. Rae J.L., Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases. Ota T., Nat. Genet. 36:40-45(2004). Martin J., Nature 432:988-994(2004).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total CLCN7 protein.
Subcellular Location	Lysosome membrane, Multi-pass membrane protein

Uniprot	P51798
Database Links	HGNC:2025 OMIM:166600 KEGG:hsa:1186 STRING:9606.ENSP00000372193 UniGene:Hs.459649
Function	Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen.
Protein Families	Chloride channel (TC 2.A.49) family, ClC-7/CLCN7 subfamily
Tissue Specificity	Brain, testis, muscle and kidney.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558336	CSB-PA212493	100ul	$297		Add to Cart

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