Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.Haas R.C., J. Biol. Chem. 265:6921-6927(1990).The MGC Project Team, Genome Res. 14:2121-2127(2004).Haas R.C., J. Biol. Chem. 264:2890-2897(1989).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human CKMT2.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
Haas R.C., J. Biol. Chem. 265:6921-6927(1990). The MGC Project Team, Genome Res. 14:2121-2127(2004). Haas R.C., J. Biol. Chem. 264:2890-2897(1989).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total CKMT2 protein.
Subcellular Location
Mitochondrion inner membrane, Peripheral membrane protein, Intermembrane side
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
Protein Families
ATP:guanido phosphotransferase family
Tissue Specificity
Sarcomere-specific. Found only in heart and skeletal muscles.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.