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Home / Antibodies

CKM Antibody / Creatine Kinase M (V8504SAF)

SKU : BHA17127547

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NSJ Bioreagents

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Mfr.No.	V8504SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Recombinant full-length CKM protein was used as the immunogen for the Creatine Kinase M antibody.
Isotype	Mouse IgG2a, kappa
Species Reactivity	Human
Note	Optimal dilution of the Creatine Kinase M antibody should be determined by the researcher.

Uniprot	P06732

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the Creatine Kinase M antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	ELISA
Description	ELISA: order Ab without BSA for coating

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/creatine-kinase-mm-antibody-ckm-3341-v8504" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127547	V8504SAF-100UG	100 ug	$499		Add to Cart

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