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Home / Primary Antibodies

Cig2 Antibody (V8291SAF)

SKU : BHA17127377

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NSJ Bioreagents

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Mfr.No.	V8291SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	Cig2 is a cyclin that functions as the catalytic subunit of cyclin-dependent kinases (Cdks) in the fission yeast Schizosaccharomyces pombe. It is a B-type, S phase cyclin that is required for both the G1/S and G2/M cell cycle transitions and is expressed in a sharp spike that peaks during the G1/S period. Cig2 binds to Cdc2 (Cdk), and the resulting Cdc2/Cig2 complex controls the G1/S transition of the cell cycle. Disruption of Cig2 delays the onset of mitosis. The expression of the Cig2 gene is dependent on Mlu1-binding factor (MBF), and the protein is destroyed during anaphase by the APC/cyclosome (APC/C) and Skp1/Cullin-1/F-box (SCF), thereby ensuring the spike expression patte of Cig2. SCF regulates Cig2 levels in a dual manner, transcriptionally and post-translationally, while APC/C only destroys the protein.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Bacterial S. pombe Cig2 purified protein was used as the immunogen for the Cig2 antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Schizosaccharomyces pombe
Note	Optimal dilution of the antibody should be determined by the researcher.

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the Cig2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	ELISA, WB
Description	ELISA (order BSA-free format for coating),Weste blot: 1-2ug/ml

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/cig2-antibody-3a11-5-v8291" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127377	V8291SAF-100UG	100 ug	$499		Add to Cart

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