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Home / Primary Antibodies

CHST8 Antibody

SKU : BHA10558303

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA035398
Alternative Names	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8; carbohydrate sulfotransferase 8; EC 2.8.2.-; GalNAc-4-O-sulfotransferase 1; GalNAc-4-ST1
Categories	Primary Antibodies
Clonality	polyclonal
Description	Catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Required for biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Only active against terminal GalNAcbeta1,GalNAcbeta. Not active toward chondroitin.Okuda T., J. Biol. Chem. 275:40605-40613(2000).Hiraoka N., Glycobiology 11:495-504(2001).Barret A., J. Biol. Chem. 280:10516-10523(2005).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human CHST8.
Involvement In Disease	Peeling skin syndrome 3 (PSS3)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Required for biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Only active against terminal GalNAcbeta1,GalNAcbeta. Not active toward chondroitin. Okuda T., J. Biol. Chem. 275:40605-40613(2000). Hiraoka N., Glycobiology 11:495-504(2001). Barret A., J. Biol. Chem. 280:10516-10523(2005).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total CHST8 protein.
Subcellular Location	Golgi apparatus membrane, Single-pass type II membrane protein

Uniprot	Q9H2A9
Database Links	HGNC:15993 OMIM:610190 KEGG:hsa:64377 STRING:9606.ENSP00000262622 UniGene:Hs.165724
Function	Catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Required for biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Only active against terminal GalNAcbeta1,GalNAcbeta. Not active toward chondroitin.
Protein Families	Sulfotransferase 2 family
Tissue Specificity	Predominantly expressed in pituitary gland. In brain, it is expressed in pituitary gland, cerebellum, medulla oblongata, pons, thalamus and spinal cord. Expressed in the epidermis. Expressed at lower level in lung, spleen, adrenal gland, placenta, prostat

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558303	CSB-PA035398	100ul	$297		Add to Cart

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