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Home / Antibodies

CHRNB1 Antibody

SKU : BHA10558189

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA437943
Alternative Names	Acetylcholine receptor subunit beta;
Categories	Primary Antibodies
Clonality	polyclonal
Description	After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.Beeson D.M.W., Nucleic Acids Res. 17:4391-4391(1989).Gomez C.M., Ann. Neurol. 39:712-723(1996).Engel A.G., Hum. Mol. Genet. 5:1217-1227(1996).
Host	Rabbit
Immunogen	Synthesized peptide derived from N-terminal of Human CHRNB1.
Involvement In Disease	Myasthenic syndrome, congenital, 2A, slow-channel (CMS2A); Myasthenic syndrome, congenital, 2C, associated with acetylcholine receptor deficiency (CMS2C)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Beeson D.M.W., Nucleic Acids Res. 17:4391-4391(1989). Gomez C.M., Ann. Neurol. 39:712-723(1996). Engel A.G., Hum. Mol. Genet. 5:1217-1227(1996).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total CHRNB1 protein.
Subcellular Location	Cell junction, synapse, postsynaptic cell membrane, Multi-pass membrane protein, Cell membrane, Multi-pass membrane protein

Uniprot	P11230
Gene Id	1140
Database Links	HGNC:1961 OMIM:100710 KEGG:hsa:1140 STRING:9606.ENSP00000304290 UniGene:Hs.330386
Function	After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Protein Families	Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) subfamily, Beta-1/CHRNB1 sub-subfamily
Weight	49,083 Da

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558189	CSB-PA437943	100ul	$297		Add to Cart

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