This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide (CGRP) and katacalcin by tissue-specific alteative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.
Formulation
In ascites with 0.09% sodium azide
Host
Mouse
Immunogen Region
A portion of amino acids 104-132 from the human protein was used as the immunogen for this CGRP antibody.
Isotype
Mouse IgM
Species Reactivity
Human
Note
Titration of the CGRP antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Uniprot
P01258
Format
Ascites
Purity
Ascites
Storage
Aliquot the CGRP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.