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Home / Antibodies

CFI Antibody

SKU : BHA10558357

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA564820
Alternative Names	C3b-INA; C3B/C4B inactivator; CFAI; complement factor I; factor I
Categories	Primary Antibodies
Clonality	polyclonal
Description	Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively.Wilson R.K., Nature 434:724-731(2005).Goldberger G., Gene 208:17-24(1998).Wang L., Zou H., J. Proteome Res. 8:651-661(2009).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human CFI.
Involvement In Disease	Hemolytic uremic syndrome atypical 3 (AHUS3); Complement factor I deficiency (CFI deficiency); Macular degeneration, age-related, 13 (ARMD13)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively. Wilson R.K., Nature 434:724-731(2005). Goldberger G., Gene 208:17-24(1998). Wang L., Zou H., J. Proteome Res. 8:651-661(2009).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total CFI protein.
Subcellular Location	Secreted, extracellular space

Uniprot	P05156
Database Links	HGNC:5394 OMIM:217030 KEGG:hsa:3426 STRING:9606.ENSP00000378130 UniGene:Hs.312485
Function	Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively.
Pathway	Complement and coagulation cascades
Protein Families	Peptidase S1 family
Tissue Specificity	Plasma.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558357	CSB-PA564820	100ul	$297		Add to Cart

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