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Home / Primary Antibodies

CERKL Antibody

SKU : BHA10557945

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA777407
Alternative Names	Ceramide kinase-like protein; CERKL;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Has no detectable ceramide-kinase activity. Overexpression of CERKL protects cells from apoptosis in oxidative stress conditions.Tuson M., Am. J. Hum. Genet. 74:128-138(2004).Bornancin F., Biochim. Biophys. Acta 1687:31-43(2005).Ota T., Nat. Genet. 36:40-45(2004).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human CERKL.
Involvement In Disease	Retinitis pigmentosa 26 (RP26)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Has no detectable ceramide-kinase activity. Overexpression of CERKL protects cells from apoptosis in oxidative stress conditions. Tuson M., Am. J. Hum. Genet. 74:128-138(2004). Bornancin F., Biochim. Biophys. Acta 1687:31-43(2005). Ota T., Nat. Genet. 36:40-45(2004).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total CERKL protein.
Subcellular Location	Cytoplasm, Nucleus, nucleolus

Uniprot	Q49MI3
Database Links	HGNC:21699 OMIM:608380 KEGG:hsa:375298 STRING:9606.ENSP00000341159 UniGene:Hs.732358
Function	Has no detectable ceramide-kinase activity. Overexpression of CERKL protects cells from apoptosis in oxidative stress conditions.
Tissue Specificity	Isoform 1 and isoform 2 are expressed in adult retina, liver and pancreas as well as in fetal brain, lung and kidney. Isoform 3 is expressed in adult retina as well as in fetal lung and liver. Isoform 4 is expressed in adult retina, lung and kidney as wel

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557945	CSB-PA777407	100ul	$297		Add to Cart

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