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Home / Primary Antibodies

CEP57 Antibody

SKU : BHA10558327

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA095230
Alternative Names	centrosomal protein of 57 kDa; FGF2-interacting protein; PIG8; testis-specific protein 57; translokin
Categories	Primary Antibodies
Clonality	polyclonal
Description	Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2, but that of FGF1.Bossard C., Nat. Cell Biol. 5:433-439(2003).Nagase T., DNA Res. 2:37-43(1995).Ota T., Nat. Genet. 36:40-45(2004)
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human CEP57.
Involvement In Disease	Mosaic variegated aneuploidy syndrome 2 (MVA2)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2, but that of FGF1. Bossard C., Nat. Cell Biol. 5:433-439(2003). Nagase T., DNA Res. 2:37-43(1995). Ota T., Nat. Genet. 36:40-45(2004)
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total CEP57 protein.
Subcellular Location	Nucleus, Cytoplasm, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome

Uniprot	Q86XR8
Database Links	HGNC:30794 OMIM:607951 KEGG:hsa:9702 STRING:9606.ENSP00000317902 UniGene:Hs.101014
Function	Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2, but that of FGF1.
Protein Families	Translokin family
Tissue Specificity	Ubiquitous.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558327	CSB-PA095230	100ul	$297		Add to Cart

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