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Home / Antibodies

CEP135 Antibody

SKU : BHA10558324

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA868990
Alternative Names	centrosomal protein 4; Cep135; CP135; KIAA0635;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for CEP250 at the centriole.Ishikawa K., DNA Res. 5:169-176(1998).Ota T., Nat. Genet. 36:40-45(2004).Andersen J.S., Nature 426:570-574(2003).
Host	Rabbit
Immunogen	Synthesized peptide derived from C-terminal of Human CEP135.
Involvement In Disease	Microcephaly 8, primary, autosomal recessive (MCPH8)
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for CEP250 at the centriole. Ishikawa K., DNA Res. 5:169-176(1998). Ota T., Nat. Genet. 36:40-45(2004). Andersen J.S., Nature 426:570-574(2003).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total CEP135 protein.
Subcellular Location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole

Uniprot	Q66GS9
Database Links	HGNC:29086 OMIM:611423 KEGG:hsa:9662 STRING:9606.ENSP00000257287 UniGene:Hs.518767
Function	Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Required for the targeting of centriole satellite proteins to centrosomes such as of PCM1, SSX2IP and CEP290 and recruitment of WRAP73 to centrioles. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for CEP250 at the centriole.
Protein Families	CEP135/TSGA10 family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558324	CSB-PA868990	100ul	$297		Add to Cart

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