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Home / Primary Antibodies

CDKAL1 Antibody

SKU : BHA10558103

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA554785
Alternative Names	CDK5 regulatory subunit-associated protein 1-like 1; CDKAL;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t6A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms2t6A) at position 37 in tRNAs that read codons beginning with adenine.Ota T., Nat. Genet. 36:40-45(2004).Mungall A.J., Nature 425:805-811(2003).Mural R.J., Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Host	Rabbit
Immunogen	Synthesized peptide derived from N-terminal of Human CDKAL.
Involvement In Disease	Diabetes mellitus, non-insulin-dependent (NIDDM)
Raised In	Rabbit
Reactivity	Human, Rat
Regulatory	RUO
Relevance	Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t6A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms2t6A) at position 37 in tRNAs that read codons beginning with adenine. Ota T., Nat. Genet. 36:40-45(2004). Mungall A.J., Nature 425:805-811(2003). Mural R.J., Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total CDKAL protein.
Subcellular Location	Endoplasmic reticulum membrane, Single-pass membrane protein

Uniprot	Q5VV42
Database Links	HGNC:21050 OMIM:125853 KEGG:hsa:54901 STRING:9606.ENSP00000274695 UniGene:Hs.657604
Function	Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
Protein Families	Methylthiotransferase family, CDKAL1 subfamily
Tissue Specificity	Expressed in pancreatic islets.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558103	CSB-PA554785	100ul	$297		Add to Cart

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