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Home / Primary Antibodies

CDK4 Antibody (RQ5377)

SKU : BHA17110050

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NSJ Bioreagents

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Mfr.No.	RQ5377
Clonality	Monoclonal
Description	The protein encoded by the CDK4 gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. (RefSeq)
Formulation	Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host	Rabbit
Immunogen Region	A synthetic peptide specific to human CDK4 was used as the immunogen for the CDK4 antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	P11802
Clone No	HOB-3

Format	Purified
Purification	Affinity purified
Storage	Store the CDK4 antibody at -20°C.

Applications	WB
Dilution	Weste blot: 1:1000-1:2000

Product Manual	Data Sheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA17110050	RQ5377	100 ul	$419		Add to Cart

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