JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Antibodies

CDH23 Antibody

SKU : BHA10558322

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

CUSABIO TECHONOLOGY LLC

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	CSB-PA207598
Alternative Names	DFNB12; USH1D; cadherin 23 C1; cadherin 23 C2; cadherin related 23
Categories	Primary Antibodies
Clonality	polyclonal
Description	Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.Bolz H., Nat. Genet. 27:108-112(2001).Clark H.F., Genome Res. 13:2265-2270(2003).Bork J.M., Am. J. Hum. Genet. 68:26-37(2001).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human CDH23.
Involvement In Disease	Usher syndrome 1D (USH1D); Usher syndrome 1D/F (USH1DF); Deafness, autosomal recessive, 12 (DFNB12); Pituitary adenoma 5, multiple types (PITA5)
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing. Bolz H., Nat. Genet. 27:108-112(2001). Clark H.F., Genome Res. 13:2265-2270(2003). Bork J.M., Am. J. Hum. Genet. 68:26-37(2001).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total CDH23 protein.
Subcellular Location	Cell membrane, Single-pass type I membrane protein

Uniprot	Q9H251
Database Links	HGNC:13733 OMIM:276900 KEGG:hsa:64072 STRING:9606.ENSP00000381768 UniGene:Hs.656032
Function	Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.
Tissue Specificity	Particularly strong expression in the retina (PubMed:11138009). Found also in the cochlea.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, IF

Description

ELISA ; IF, IF ; ELISA

Dilution

IF	1:100-1:500

Tested Application

ELISA,IF;IF:1:100-1:500

Datasheet
ELISA Protocol
Immunofluorescence (IF) Protocol

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHA10558322	CSB-PA207598	100ul	$297		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.