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Home / Primary Antibodies

CDCP1 Antibody

SKU : BHA10557571

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA442968
Alternative Names	TRASK; SIMA135;
Categories	Primary Antibodies
Clonality	polyclonal
Description	May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.Scherl-Mostageer M., Sommergruber W., Abseher R., Hauptmann R., Ambros P., Schweifer N.Oncogene 20:4402-4408(2001) Bhatt A.S., Erdjument-Bromage H., Tempst P., Craik C.S., Moasser M.M.Oncogene 24:5333-5343(2005)Xia Y., Gil S.G., Carter W.G.J. Cell Biol. 132:727-740(1996)
Host	Rabbit
Immunogen	Peptide sequence around aa.828~832( T-Q-E-P-M) derived from Human CDCP1(CD318).
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis. Scherl-Mostageer M., Sommergruber W., Abseher R., Hauptmann R., Ambros P., Schweifer N. Oncogene 20:4402-4408(2001) Bhatt A.S., Erdjument-Bromage H., Tempst P., Craik C.S., Moasser M.M.Oncogene 24:5333-5343(2005) Xia Y., Gil S.G., Carter W.G.J. Cell Biol. 132:727-740(1996)
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous level of total CDCP1(CD318) protein.
Subcellular Location	Isoform 1: Cell membrane, Single-pass membrane protein

Uniprot	Q9H5V8
Database Links	HGNC:24357 OMIM:611735 KEGG:hsa:64866 STRING:9606.ENSP00000296129 UniGene:Hs.476093
Function	May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.
Tissue Specificity	Highly expressed in mitotic cells with low expression during interphase. Detected at highest levels in skeletal muscle and colon with lower levels in kidney, small intestine, placenta and lung. Up-regulated in a number of human tumor cell lines, as well a

Buffer	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Purity	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:1000

Tested Application

ELISA,WB;WB:1:500-1:1000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557571	CSB-PA442968	100ul	$297		Add to Cart

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