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Home / Antibodies

CDCA2 Antibody

SKU : BHA10558101

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA124174
Alternative Names	FLJ25804; MGC129906; MGC129907; cell division cycle associated 2;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.Walker M.G., Curr. Cancer Drug Targets 1:73-83(2001).Ota T., . Genet. 36:40-45(2004).Olsen J.V., Cell 127:635-648(2006).
Host	Rabbit
Immunogen	Synthesized peptide derived from C-terminal of Human CDCA2.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates. Walker M.G., Curr. Cancer Drug Targets 1:73-83(2001). Ota T., . Genet. 36:40-45(2004). Olsen J.V., Cell 127:635-648(2006).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total CDCA2 protein.
Subcellular Location	Nucleus

Uniprot	Q69YH5
Database Links	HGNC:14623 KEGG:hsa:157313 STRING:9606.ENSP00000328228 UniGene:Hs.33366
Function	Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.
Tissue Specificity	Ubiquitously expressed.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558101	CSB-PA124174	100ul	$297		Add to Cart

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