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Home / Antibodies

CDC42EP2 Antibody

SKU : BHA10558318

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA546490
Alternative Names	Cdc42 effector protein 2; Binder of Rho GTPases 1;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.Guru S.C., Genome Res. 7:725-735(1997).Joberty G., Mol. Cell. Biol. 19:6585-6597(1999).Hirsch D.S., J. Biol. Chem. 276:875-883(2001)
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human BORG1.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner. Guru S.C., Genome Res. 7:725-735(1997). Joberty G., Mol. Cell. Biol. 19:6585-6597(1999). Hirsch D.S., J. Biol. Chem. 276:875-883(2001)
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total BORG1 protein.
Subcellular Location	Endomembrane system, Peripheral membrane protein, Cytoplasm, cytoskeleton

Uniprot	O14613
Database Links	HGNC:16263 OMIM:606132 KEGG:hsa:10435 STRING:9606.ENSP00000279249 UniGene:Hs.343380
Function	Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.
Protein Families	BORG/CEP family
Tissue Specificity	Highly expressed in the heart. Weakly expressed in the pancreas and liver.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558318	CSB-PA546490	100ul	$297		Add to Cart

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