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CDC27 Antibody

SKU : BHA10558099

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA200778
Alternative Names	CDC27Hs; Cell division cycle protein 27 homolog; H-NUC;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.Tugendreich S., Proc. Natl. Acad. Sci. U.S.A. 90:10031-10035(1993).Chen P.L., Cell Growth Differ. 6:199-210(1995).Kraft C., EMBO J. 22:6598-6609(2003).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human H-NUC.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Tugendreich S., Proc. Natl. Acad. Sci. U.S.A. 90:10031-10035(1993). Chen P.L., Cell Growth Differ. 6:199-210(1995). Kraft C., EMBO J. 22:6598-6609(2003).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total H-NUC protein.
Subcellular Location	Nucleus

Uniprot	P30260
Gene Id	996
Database Links	HGNC:1728 OMIM:116946 KEGG:hsa:996 STRING:9606.ENSP00000434614 UniGene:Hs.463295
Function	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins
Pathway	Cell cycle Ubiquitin mediated proteolysis
Protein Families	APC3/CDC27 family
Weight	92,612 Da

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558099	CSB-PA200778	100ul	$297		Add to Cart

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