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Home / Antibodies

CD8A Antibody (V2043CF488)

SKU : BHA17123356

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NSJ Bioreagents

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Mfr.No.	V2043CF488-100T
Clonality	Monoclonal (mouse origin)
Description	CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.
Formulation	500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Host	Mouse
Immunogen Region	Human recombinant protein was used as the immunogen for this CD8a antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the CD8a antibody should be determined by the researcher.

Uniprot	P01732

Format	CF488 Conjugate
Purity	Protein G affinity chromatography
Storage	Store the CD8a antibody at 2-8oC, protected from light.

Applications	FACS, IF
Description	Flow cytometry: 5ul per test per one million cells in 0.1ml or 5ul per 100ul of whole blood,Immunofluorescence: 1:50-1:100

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17123356	V2043CF488-100T	100 Tests	$499		Add to Cart

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