FCAR, Receptor for Fc fragment of IGA, is also known as CD89. It is a glycoprotein of 50-100 kD present on a number of cell types, including neutrophils, monocytes, macrophages, and eosinophils. CD89 interacts with aggregated IgAs (but not IgGs), such as IgA coated on the surface of an invading microorganism, and mediates several immunologic defense processes such as phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
An amino acid sequence from the middle of human CD89 (EFVIDHMDANKAGRYQCQ) was used as the immunogen for this CD89 antibody.
Isotype
IgG
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Uniprot
P24071
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the CD89 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.