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Home / Primary Antibodies

CD86 Antibody (V2989SAF)

SKU : BHA17124582

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NSJ Bioreagents

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Mfr.No.	V2989SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	CD86 is a receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. (UniProt)
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Recombinant human full-length protein was used as the immunogen for the CD86 antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human, Mouse, Rat
Note	Optimal dilution of the CD86 antibody should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris buffer with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 min.

Uniprot	P42081

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the CD86 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IF, IHC-P
Description	Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 2-4ug/ml for 30 min at RT

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17124582	V2989SAF-100UG	100 ug	$499		Add to Cart

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