Recognizes a protein of 74kDa, identified as CD84 (Workshop V; Code A085, C057). It is expressed on mature B cells and on B-cell lines, including pre-B-cell lines, but not on plasma cell lines. Immunohistochemical studies demonstrated that CD84 strongly expressed on tissues macrophages. CD84 is also highly expressed on platelets and, at low levels on peripheral blood T cells. It is a highly N-glycosylated protein and belongs to immunoglobulin superfamily. It may play a role in leukocyte activation.
Formulation
1 mg/ml in 1X PBS; BSA free, sodium azide free
Host
Mouse
Immunogen Region
Spleen cells of a patient with hairy cell leukemia were used as the immunogen for the CD84 antibody.
Isotype
Mouse IgG1, kappa
Species Reactivity
Human
Note
Optimal dilution of the CD84 antibody should be determined by the researcher.
Uniprot
Q9UIB8
Format
Purified
Purity
Protein G affinity chromatography
Storage
Store the CD84 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).