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Home / Antibodies

CD68 Antibody (V3943SAF)

SKU : BHA17125754

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NSJ Bioreagents

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Mfr.No.	V3943SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	CD68 (Cluster of Differentiation 68) is a protein highly expressed by cells in the monocyte lineage (e.g., monocytic phagocytes, osteoclasts), by circulating macrophages, and by tissue macrophages (e.g., Kupffer cells, microglia). Human CD68 is a transmembrane glycoprotein, heavily glycosylated in its extracellular domain, with a molecular weight of 110 kD. Immunohistochemistry can be used to identify the presence of CD68, which is found in the cytoplasmic granules of a range of different blood cells and myocytes. It is particularly useful as a marker for the various cells of the macrophage lineage, including monocytes, histiocytes, giant cells, Kupffer cells, and osteoclasts. This allows it to be used to distinguish diseases of otherwise similar appearance, such as the monocyte/macrophage and lymphoid forms of leukaemia (the latter being CD68 negative). Its presence in macrophages also makes it useful in diagnosing conditions related to proliferation or abnormality of these cells, such as malignant histiocytosis, histiocytic lymphoma, and Gaucher's disease. (Wiki)
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A portion of amino acids 150-221 from the human protein was used as the immunogen for the CD68 antibody.
Isotype	Mouse IgG2c, kappa
Species Reactivity	Human
Note	The stated application concentrations are suggested starting points. Titration of the CD68 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Uniprot	P34810

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the CD68 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17125754	V3943SAF-100UG	100 ug	$499		Add to Cart

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