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Home / Primary Antibodies

CD63 Antibody / LAMP-3 (V8258SAF)

SKU : BHA17127350

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NSJ Bioreagents

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Mfr.No.	V8258SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	This MAb recognizes protein of 26kDa-60kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A recombinant human partial protein (amino acids 100-197) was used as the immunogen for the CD63 antibody.
Isotype	Mouse IgG2b, kappa
Species Reactivity	Human, Mouse
Note	Optimal dilution of the antibody should be determined by the researcher.

Uniprot	P08962

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the CD63 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	WB, IHC-P
Description	Weste blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/cd63-antibody-lamp3-2788-v8258" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127350	V8258SAF-100UG	100 ug	$499		Add to Cart

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