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Home / Primary Antibodies

CD63 Antibody / LAMP-3 (V2071CF488)

SKU : BHA17123389

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NSJ Bioreagents

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Mfr.No.	V2071CF488-100T
Clonality	Monoclonal (mouse origin)
Description	This MAb recognizes protein of 26kDa-60kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
Formulation	500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Host	Mouse
Immunogen Region	Full length human CD63 was used as the immunogen for this antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human, Mouse
Note	Optimal dilution of the CD63 antibody should be determined by the researcher.

Uniprot	P08962

Format	CF488 Conjugate
Purity	Protein G affinity chromatography
Storage	Store the CD63 antibody at 2-8oC, protected from light.

Applications	FACS, IF
Description	Flow cytometry: 5ul per test per one million cells in 0.1ml or 5ul per 100ul of whole blood,Immunofluorescence: 1:50-1:100

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17123389	V2071CF488-100T	100 Tests	$499		Add to Cart

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