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Home / Primary Antibodies

CD63 Antibody / LAMP-3 (V2070PE)

SKU : BHA17123386

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NSJ Bioreagents

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Mfr.No.	V2070PE-100T
Clonality	Monoclonal (mouse origin)
Description	The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
Formulation	500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Host	Mouse
Immunogen Region	The smooth plasma membrane fraction of MeWo cells was used as the immunogen for this CD63 antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human and Mouse. Other species not known.
Note	The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.

Format	PE Conjugate
Purity	Protein G purified antibody
Storage	Store the CD63 antibody at 2-8°C. Conjugate is light sensitive, store in the dark.

Applications	FACS, IF
Description	Flow Cytometry: 5ul/test/million cells or 5ul/test/100ul of whole blood,Immunofluorescence: 1:50-1:100 for 30 minutes at RT

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17123386	V2070PE-100T	100 Tests	$499		Add to Cart

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