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Home / Antibodies

CD59 Antibody (RQ5418)

SKU : BHA17110084

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NSJ Bioreagents

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Mfr.No.	RQ5418
Clonality	Monoclonal
Description	This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alteatively spliced transcript variants, which encode the same protein, have been identified for this gene. (RefSeq)
Formulation	Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host	Rabbit
Immunogen Region	A synthetic peptide specific to human CD59 was used as the immunogen for the CD59 antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	P13987
Clone No	AABE-3

Format	Purified
Purification	Affinity purified
Storage	Store the CD59 antibody at -20°C.

Applications	WB
Dilution	Weste blot: 1:1000-1:5000

Product Manual	Data Sheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA17110084	RQ5418	100 ul	$419		Add to Cart

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