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Home / Primary Antibodies

CD58 Antibody

SKU : BHA10558472

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA205850
Alternative Names	Lymphocyte function-associated antigen 3; Ag3; Surface glycoprotein LFA-3; CD58 antigen;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.Wallner B.P., J. Exp. Med. 166:923-932(1987).Wallich R., J. Immunol. 160:2862-2871(1998).Ota T., Nat. Genet. 36:40-45(2004).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human LFA3.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Wallner B.P., J. Exp. Med. 166:923-932(1987). Wallich R., J. Immunol. 160:2862-2871(1998). Ota T., Nat. Genet. 36:40-45(2004).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total LFA3 protein.
Subcellular Location	Isoform 1: Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Isoform 2: Cell membrane, Lipid-anchor, GPI-anchor

Uniprot	P19256
Database Links	HGNC:1688 OMIM:153420 KEGG:hsa:965 STRING:9606.ENSP00000358501 UniGene:Hs.34341
Function	Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558472	CSB-PA205850	100ul	$297		Add to Cart

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