Reacts with human CD48, a 45kDa glycosyl phophatidyl-inositol (GPI)-anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of the markers for detecting the defects of GPI anchoring structure on the patients with paroxysmal noctual hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2.
Formulation
1 mg/ml in 1X PBS; BSA free, sodium azide free
Host
Mouse
Immunogen Region
Human peripheral blood lymphocytes were used as the immunogen for the CD48 antibody.
Isotype
Mouse IgG2a, kappa
Species Reactivity
Human
Note
Optimal dilution of the CD48 antibody should be determined by the researcher.
Uniprot
P09326
Format
Purified
Purity
Protein G affinity chromatography
Storage
Store the CD48 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).