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Home / Primary Antibodies

CD45 Monoclonal Antibody

SKU : BHA13715078

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Abbkine Scientific Co., Ltd.

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Mfr.No.	ABM0014
Alternative Names	PTPRC; CD45; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; L-CA; T200; CD45
Background	Protein tyrosine phosphatase, receptor type C encoded by PTPRC is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of PTPRC, which encode distinct isoforms, have been reported.
Clonality	Monoclonal
Description	Mouse Anti-CD45 Monoclonal Antibody
Formulation	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen, Liquid solution
Host	Mouse
Immunogen	Synthetic Peptide
Immunogen Region	Synthetic Peptide
Isotype	Mouse IgG1
Molecular Weight	147 KD
Others	The antibody detects endogenous CD45 proteins.
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Reactivity	Human
Tag	Receptor-type tyrosine-protein phosphatase C
Note	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:2000), IF (1:50-1:200), IHC-P (1:50-1:300).

Accession Number	P08575
Gene Id	5788, 5788

Concentration	1 mg/ml, 1 mg/ml
Purification	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen, The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
Storage Buffer	PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage Instructions	Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Applications	WB, IF, IHC-P

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA13715078	ABM0014	100 uL	$229		Add to Cart

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