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Home / Primary Antibodies

CD45 Antibody (Leukocyte marker) (V8396SAF)

SKU : BHA17127461

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NSJ Bioreagents

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Mfr.No.	V8396SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alteative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Human recombinant full-length protein was used as the immunogen for the CD45 antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the CD45 antibody should be determined by the researcher.

Uniprot	P08575

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the CD45 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	FACS, WB
Description	Flow cytometry: 1-2ug/million cells,Weste blot: 1-2ug/ml

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/cd45-antibody-ptprc-1666-v8396" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127461	V8396SAF-100UG	100 ug	$499		Add to Cart

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