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Home / Primary Antibodies

CD44 Antibody / HCAM (V7008SAF)

SKU : BHA17125843

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NSJ Bioreagents

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Mfr.No.	V7008SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alteative splicing and post-translational modification events. Receptor for LGALS9; the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (By similarity). (UniProt)
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Purified human protein was used as the immunogen for the CD44 antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Titering of the CD44 antibody may be required for optimal performance.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Uniprot	P16070

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the CD44 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17125843	V7008SAF-100UG	100 ug	$499		Add to Cart

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