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Home / Antibodies

CD37 Antibody (V3006SAF)

SKU : BHA17124605

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NSJ Bioreagents

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Mfr.No.	V3006SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	Recognizes a protein of 33-55kDa, identified as CD37 (Workshop V; Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg+) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin'' lymphoma (B-NHL).
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the CD37 antibody.
Isotype	Mouse IgG2b, kappa
Species Reactivity	Human
Note	Optimal dilution of the CD37 antibody should be determined by the researcher.

Uniprot	P11049

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the CD37 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	Functional studies, FACS, IF
Description	Functional studies (order BSA/sodium azide-free format),Flow cytometry: 0.5-1ug/million cells,Immunofluorescence: 0.5-1ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17124605	V3006SAF-100UG	100 ug	$499		Add to Cart

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